Murine T-Lymphomas Corresponding to the Immature CD4-8+Thymocyte Subset
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چکیده
منابع مشابه
Murine T-Lymphomas Corresponding to the Immature CD4-8+ Thymocyte Subset
N-methyl-N-nitrosourea induces murine CD4-8+ T-lymphomas that express high levels of J11d and low levels of CD5 antigens, a phenotype characteristic of immature CD4-8+ thymocytes. This assignment is supported by the fact that CD4-8+ lymphoma cell lines acquire CD4 expression after intrathymic (i.t.) transfer, a finding consistent with the established precursor potential of the normal immature C...
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A panel of 20 murine CD4+ clones was examined for the presence of surface membrane receptors for IgA, IgM, IgD, IgE, and IgG. High level expression of multiple Fc receptors (FcRs) was found on all Th2 clones. FcR expression was low or undetected on the Th1 clones. The preferential expression of FcR on activated Th2 cells suggests potential mechanisms for immunoregulatory interactions with B cells.
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ژورنال
عنوان ژورنال: Developmental Immunology
سال: 1991
ISSN: 1044-6672
DOI: 10.1155/1991/98963